Correlational studies on insulin resistance and leptin gene polymorphisms in peritoneal dialysis patients
نویسندگان
چکیده مقاله:
Objective(s):The aim of the study was to investigate the relationship between insulin resistance (IR) and leptin (LEP) gene polymorphisms in peritoneal dialysis (PD) patients. Materials and Methods: From July 1, 2011 to August 1, 2011, patients who received chronic PD were chosen and divided into three groups (DM, high HOMR-IR, and low HOMR-IR). Two PCR products of LEP were sequenced and aligned and the distribution of polymorphisms was analyzed using χ2 analysis. In addition, serum leptin level, PD conditions, and biochemical parameters according to different genotype of G-2548A and A19G were statistically analyzed (P-value
منابع مشابه
correlational studies on insulin resistance and leptin gene polymorphisms in peritoneal dialysis patients
objective(s):the aim of the study was to investigate the relationship between insulin resistance (ir) and leptin (lep) gene polymorphisms in peritoneal dialysis (pd) patients. materials and methods: from july 1, 2011 to august 1, 2011, patients who received chronic pd were chosen and divided into three groups (dm, high homr-ir, and low homr-ir). two pcr products of lep were sequenced and aligne...
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عنوان ژورنال
دوره 18 شماره 9
صفحات 878- 886
تاریخ انتشار 2015-09-01
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